Pro-proliferative Factor KLF5 Becomes Anti-proliferative in Epithelial Homeostasis upon Signaling-mediated Modification
نویسندگان
چکیده
منابع مشابه
Anti-Proliferative, Anti-Oxidant and Pro-apoptotic Effect of Alcoholic Extract of lavender in HepG2 cell lines
Background: Liver cancer is the second leading cause of cancer deaths in the world and is therefore a major public health challenge. In recent years, many of the drugs used in the treatment of many malignancies and cancers have been of plant origin. Lavender extract has been shown to have therapeutic effects in various cancers. Therefore, the biological effects of ethanolic extract of lavender ...
متن کاملImproved anti-proliferative effect of doxorubicin-containing polymer nanoparticles upon surface modification with cationic groups.
Polymer nanoparticles (PNPs) possessing a high density of drug payload have been successfully stabilized against aggregation in biological buffers after amine modification, which renders these PNPs positively charged. The resulting charge-stabilized PNPs retain their original narrow particle size distributions and well-defined spherical morphologies. This stabilization allows these PNPs to have...
متن کاملRepression of anti-proliferative factor Tob1 in osteoarthritic cartilage
Osteoarthritis is the most common degenerative disorder of the modern world. However, many basic cellular features and molecular processes of the disease are poorly understood. In the present study we used oligonucleotide-based microarray analysis of genes of known or assumed relevance to the cellular phenotype to screen for relevant differences in gene expression between normal and osteoarthri...
متن کاملAnti-proliferative, pro-apoptotic and anti-invasive effect of EC/EV system in human osteosarcoma
Osteosarcoma is the most common and aggressive bone tumor in children. The Endocannabinoid/Endovanilloid system has been proposed as anticancer target in tumor of different origins. This system is composed of two receptors (CB1 and CB2), the Transient Potential Vanilloid 1 (TRPV1) channel and their ligands and enzymes. CB1 is expressed mainly in central nervous system while CB2 predominantly on...
متن کاملAnti-Angiogenic and Anti-Proliferative Effects of Physalis Alkekengi Hydroalcholic Extract on Breast Cancer in Mice
Background & Objective: The Physalis alkekengi is a herbaceous plant belonging to Solanaceae family. According to research, this plant can help inhibit cancer cell growth. Materials & Methods: In this study, the extract of Physalis alkekengi was used to suppress angiogenesis in Balb/c mice. First, the MC4L2 cells were injected in the mice breastbone and the tumor began to grow in this area, th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.m806270200